Anesthetic Cardioprotection: The Role of Adenosine
نویسندگان
چکیده
منابع مشابه
A physiological role of the adenosine A3 receptor: sustained cardioprotection.
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Ischemic injury to the myocardium is a leading cause of morbidity and mortality around the globe.1 It is worth remembering, however, that this insult to the heart emerged only in the last few centuries, an instant in time from an evolutionary perspective. Thus, any cardioprotective responses to ischemic injury undoubtedly evolved for an entirely different purpose. Beyond pure academic interest,...
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With aging, it appears the heart's ability to withstand injury declines markedly. Unfortunately, the incidence of ischemic disorders increases dramatically with age. Though the genesis of the ischemia-intolerant phenotype is incompletely understood (and likely multi-factorial), it may involve changes in intrinsic cardioprotective responses. In this respect we and others have interrogated the ro...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Design
سال: 2014
ISSN: 1381-6128
DOI: 10.2174/1381612820666140204102524